The Controlled Release Society has been governed by outstanding leaders from academia and industry. Their foresight and guidance have contributed tremendously to the successes of CRS.
- 1978-1979 Frank Harris
- 1979-1980 Frank Harris
- 1980-1981 George Janes
- 1981-1982 Richard Baker
- 1982-1983 Danny Lewis
- 1983-1984 Agis Kydonieus
- 1984-1985 Zack Mansdorf
- 1985-1986 Joseph Bakan*
- 1986-1987 Theodore Roseman
- 1987-1988 Nicholas Peppas
- 1988-1989 Lynda Sanders
- 1989-1990 Jorge Heller*
- 1990-1991 Joseph Robinson*
- 1991-1992 Robert Langer
- 1992-1993 Vincent Lee
- 1993-1994 Gordon Amidon
- 1994-1995 Hans Junginger
- 1995-1996 Jindrich Kopecek
- 1996-1997 Tsuneji Nagai
- 1997-1998 Ronald Siegel
- 1998-1999 Thomas Kissel
- 1999-2000 Gary Cleary
- 2000-2001 Richard Guy
- 2001-2002 Kinam Park
- 2002-2003 Alexander Florence
- 2003-2004 J. Anderson
- 2004-2005 Jennifer Dressman
- 2005-2006 Vladimir Torchilin
- 2006-2007 Randy Mrsny
- 2007-2008 Susan Cady
- 2008-2009 Lisbeth Ilum
- 2009-2010 Diane Burgess
- 2010-2011 Mark Tracy
- 2011-2012 Martyn Davies
- 2012-2013 Kazunori Kataoka
- 2013-2014 Ian Tucker
- 2014-2015 Arthur Tipton
- 2015-2016 Debra Bingham
- 2016-2017 Ruth Schmid
- 2017-2018 Tamara Minko
- 2018-2019 Maria Jose Alonso
- 2019-2020 Justin Hanes
- 2020-2021 Yvonne Perrie
- 2021-2022 Ben Boyd
- 2022-2023 Christine Allen
- 2023-2024- Twan Lammers
*deceased