CT/Optical Liposomes for High Accuracy Tumor Resection Using Image-Guided Surgery

Category

Imaging and Characterization Techniques for Drug Delivery: Systems and Targeted Drug Delivery

Year

2013

Authors

Jinzi Zheng, Raquel De Souza, Mengqing Li, Michael Dunne, Christine Allen, David A. Jaffray

Institutions

Princess Margaret Cancer Centre, Toronto, Ontario, M5G 2M9, Canada; University of Toronto, Toronto, Ontario, M5S 3M2, Canada

Summary

A dual-modality computed tomography (CT) and near-infrared (NIR) fluorescence liposome agent suitable for image-guided surgery applications was shown to accumulate in primary and metastatic tumor lesions of mouse xenograft models of human cancer.