Category
Nanoparticles in Tumor Treatment
Year
2014
Institutions
Center for Bioanoengineering and State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China
Summary
The cancer drug delivery process is a cascade of five steps consisting of circulation in blood, accumulation and penetration into the tumor, cellular internalization and intracellular drug release or the CAPIR cascade. Thus, the most challenging aspect of cancer nanomedicine design is the integration and synchronization of all functions required to accomplish the CAPIR cascade into one system, particularly, many of which are in opposite in different CAPIR steps.
