Category
Topical/Transdermal Drug Delivery
Year
2013
Institutions
Pharmacy Department, Free University, Berlin, 12169, Germany; PharmaSol GmbH, Berlin, 12307 Berlin, Germany
Summary
Increasing dermal penetration/permeation is still a challenge for many cosmetic actives and drugs. An overview is presented to exploit physical principles for delivery improvement, e.g. ranging from simple occlusion to generated supersaturation effects. The principles are exploited in combination with dermal nanocarriers. In contrast to chemical enhancers, these principles have no/little regulatory hurdles.