RNAdjuvant®, a novel RNA-based immunomodulator, combines strong immunostimulatory capacities with a favourable safety profile

Category
Proteins, Peptides, and Vaccines
Year
2014
Authors
Patrick Baumhof, Regina Heidenreich, Birgit Scheel, Söhnke Voss, Karl-Josef Kallen, Mariola Fotin-Mleczek
Institutions
CureVac GmbH, Tübingen, 72076, Germany
Summary

CureVac has developed a novel nanoparticular RNA-based adjuvant formulation with strong immunostimulatory properties. RNAdjuvant® can be combined with different antigenic formats, like recombinant proteins and peptides, resulting in dramatically increased immunogenicity of these vaccines.