In vivo enhancement of transscleral penetration of macromolecules by low-intensity and low-frequency ultrasound

This study aims to determine in vivo effectiveness of low-frequency ultrasound in mediating the transport of macromolecules to posterior segment of the eye via transscleral route. Investigations were carried out to examine, if any, damage is caused by ultrasound at the tested operation parameters on the posterior ocular tissues and visual function.