Annual Meeting Archives

2018

A Strong Transfection Activity Obtained With The Association Of β-glucan To Polymer Polyplexes For A Hepatitis B DNA Vaccine
Category:
Nucleic Acid Delivery
Presenters:
Olga Borges
Authors:
E. Soares, R. Cordeiro, H. Faneca, <b>O. Borges</b>; Univ. of Coimbra, Coimbra, Portugal
Institutions:
University of Coimbra
A Thermo-responsive Elastin-like Polypeptide Carrier For Cyclosporine A
Category:
Parenteral Controlled Release
Presenters:
J. Andrew MacKay
Authors:
H. Guo, S. F. Hamm-Alvarez, <b>J. MacKay</b>; Univ. of Southern California, Los Angeles, CA
Institutions:
University of Southern California
A Tumor-activatable Theranostic Nanomedicine For NIR Fluorescence-guided Surgery And Phototherapy
Category:
Micro- and nanoparticle Delivery
Presenters:
Olena Taratula
Authors:
<b>O. Taratula</b>, O. Taratula, X. Li, C. Schumann, H. Albarqi, A. Alani, S. Bracha, M. Milovancev; Oregon State Univ., Portland, OR
Institutions:
Oregon State University
Absorption And Antisecretory Activity In Conscious Rats After Administration Of Esomeprazole Immediate Release Tablets
Category:
Oral Delivery for Food and Pharma
Presenters:
Alessandra Rossi
Authors:
<b>A. Rossi</b>, G. Adorni, E. Quarta, P. Colombo; Univ. of Parma, Parma, Italy
Institutions:
University of Parma
Activation of Mesenchymal Stem Cells for Ischemic Tissue Repair
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Eunice Leong
Authors:
<b>E. Leong</b><sup>1</sup>, E. Ko<sup>1</sup>, Y-F. Wu<sup>1</sup>, S. Dvoretskiy<sup>1</sup>, J. Teo<sup>1</sup>, H. Jeon<sup>2</sup>, M. Boppart<sup>1</sup>, Y. Yang<sup>3</sup>, H. Kong<sup>1</sup>; <sup>1</sup>Univ. of Illinois, Urbana-Champaign, Urbana, IL, <sup>2</sup>Korean Inst. of Sci. and Technology, Seoul, Korea, Republic of, <sup>3</sup>Inst. of Bioengineering and Nanotechnology, Singapore, Singapore
Institutions:
University of Illinois, Urbana-Champaign
Active Freeze Dried Versus Spray Dried Nanocrystal-based Powders: Flow Behavior And Dissolution Performance
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Antoine Touzet
Authors:
<b>A. Touzet</b><sup>1</sup>, C. Herkenne<sup>2</sup>, A. Lamprecht<sup>3</sup>, Y. Pellequer<sup>1</sup>; <sup>1</sup>Bourgogne Franche-Comté Univ., Besançon, France, <sup>2</sup>Debiopharm Res. and Manufacturing, Martigny, Switzerland, <sup>3</sup>Inst. of Pharmacy, Bonn, Germany
Institutions:
Bourgogne Franche-Comté University
Adipose Derived Primary Human Mesenchymal Stem Cell Integrin Determination For Designing An Effective Biofunctionalization Strategy
Category:
Micro- and nanoparticle Delivery
Presenters:
Rosa Maria Hernandez
Authors:
A. Gonzalez-Pujana<sup>1</sup>, M. García-Hernando<sup>2</sup>, F. Benito-López<sup>2</sup>, M. Martinez de Pancorbo<sup>3</sup>, J. Pedraz<sup>1</sup>, M. Igartua<sup>1</sup>, E. Santos-Vizcaino<sup>1</sup>, L. Basabe-Desmonts<sup>2</sup>, <b>R. Hernandez</b><sup>1</sup>; <sup>1</sup>NanoBioCel Group, Lab. of Pharmaceutics, Sch. of Pharmacy, Univ. of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain, <sup>2</sup>Microfluidics Cluster UPV/EHU, Lascaray Res. Ctr., Univ. of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain, <sup>3</sup>BIOMICs Res. Group, Lascaray Res. Ctr., Univ. of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain
Institutions:
NanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV/EHU)
Advanced Fluorescent pH-Sensitive PLGA Particles for Controlled Targeted Therapeutic Delivery and Mapping Microenvironmental Biochemical Parameters
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Veeren Chauhan
Authors:
<b>V. M. Chauhan</b>, M. Al-Natour, A. A. Selo, D. J. Scurr, R. Markus, C. Alexander, J. W. Aylott; Univ. of Nottingham, Nottingham, United Kingdom
Institutions:
University of Nottingham
Aerosol Delivery of Supramolecular Drug Amphiphile Nanofilaments for Local Lung Cancer Treatment
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Caleb Anderson
Authors:
<b>C. F. Anderson</b>, H. Cui; Johns Hopkins Univ., Baltimore, MD
Institutions:
Johns Hopkins University
Alginates Particles For Dry Powder inhalations
Category:
Micro- and nanoparticle Delivery
Presenters:
MOHAMAMD ALYAMI
Authors:
<b>M. ALYAMI</b>; ASTON Univ., BIRMINGHAM, United Kingdom
Institutions:
ASTON UNIVERSITY
Allergen-free Pollen Shell As A Novel Biomaterial For Oral Vaccine Delivery: Development, Characterization, In Vivo Efficacy, And Mechanistic Insight
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Md Uddin
Authors:
<b>M. J. Uddin</b>, H. S. Gill; Texas Tech Univ., Lubbock, TX
Institutions:
Texas Tech University
Amelioration Of Carbon Tetrachloride-induced Hepatic Fibrosis In Mice By Targeting Activated Hepatic Stellate Cells With A Docetaxel-carboxymethylcellulose Nanoparticle
Category:
Micro- and nanoparticle Delivery
Presenters:
Chih-Chun Chang
Authors:
<b>C-C. Chang</b><sup>1</sup>, Y. Yang<sup>2</sup>, D-Y. Gao<sup>1</sup>, H-T. Cheng<sup>3</sup>, B. Hoang<sup>2</sup>, P-H. Chao<sup>1</sup>, L-H. Chen<sup>1</sup>, J. Bteich<sup>2</sup>, T. Chiang<sup>1</sup>, J-Y. Liu<sup>1</sup>, S-D. Li<sup>2</sup>, Y. Chen<sup>1</sup>; <sup>1</sup>Natl. Tsing-Hua Univ., Hsinchu, Taiwan, <sup>2</sup>The Univ. of British Columbia, Vancouver, BC, Canada, <sup>3</sup>Natl. Taiwan Univ. Hosp. Hsinchu Branch, Hsinchu, Taiwan
Institutions:
National Tsing-Hua University
Amino-functionalized Mesoporous Silica Nanoparticles For The Topical Delivery Of Dexamethasone
Category:
Topical and Transdermal Delivery
Presenters:
Aliyah Almomen
Authors:
<b>A. Almomen</b><sup>1</sup>, A. El-Toni<sup>2</sup>, A. Alhowyan<sup>3</sup>, M. Badran<sup>3</sup>, A. Alshamsan<sup>3</sup>, M. Alkholief<sup>3</sup>; <sup>1</sup>Nanomedicine Res. Unit Dept. of Pharmaceutics; Dept. of Pharmaceutical Chemistry, Coll. of Pharmacy 11451, Riyadh, Saudi Arabia, <sup>2</sup>King Abdullah Inst. for Nanotechnology, King Saud Univ., Riyadh 11451, Saudi Arabia and Central Metallurgical Res. and Dev. Inst., CMRDI 11421, Cairo, Egypt, <sup>3</sup>Nanomedicine Res. Unit, Dept. of Pharmaceutics, Coll. of Pharmacy 11451, Riyadh, Saudi Arabia
Institutions:
Nanomedicine Research Unit Department of Pharmaceutics; Department of Pharmaceutical Chemistry, College of Pharmacy 11451
An Improvement Of Anti-angiogenic Therapy Achieved By Bevacizumab Delivery Through Plga Nanocarriers
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Flavia Sousa
Authors:
<b>F. Sousa</b><sup>1</sup>, A. Cruz<sup>2</sup>, P. Fonte<sup>3</sup>, I. Mendes-Pinto<sup>2</sup>, T. Neves-Petersen<sup>4</sup>, B. Sarmento<sup>1</sup>; <sup>1</sup>i3s, Inst. de Investigação e Inovação em Saúde, Porto, Portugal, <sup>2</sup>INL, Intl. Nanotechnology Lab., Braga, Portugal, <sup>3</sup>CBIOS, Univ.e Lusófona Res. Ctr. for BioSci.s & Hlth.Technologies, Lisboa, Portugal, <sup>4</sup>Aalborg Univ., Aalborg, Denmark
Institutions:
i3s, Instituto de Investigação e Inovação em Saúde
An Injectable Hyaluronan-Collagen Matrix For Controlled Delivery Of Oligonucleotides
Category:
Nucleic Acid Delivery
Presenters:
Michael Onorato
Authors:
<b>M. V. Onorato</b>; BioTime Inc., Alameda, CA
Institutions:
BioTime Inc.
An Investigation Into The Effects Of Functional Additives On The Release Behaviour Of Controlled Release Solid Dispersions Prepared By Hot Melt Extrusion
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Fahad Alqahtani
Authors:
<b>F. Alqahtani</b>; Univ. of East Anglia, Norwich, United Kingdom
Institutions:
University of East Anglia
An Isolated Perfused Rat Lung Model For Studying Controlled And Targeted Release Of Fasudil, An anti-PAH drug, From Peptide Grafted Liposomal Formulations
Category:
Micro- and nanoparticle Delivery
Presenters:
Ali keshavarz
Authors:
<b>A. keshavarz</b>, A. Alobaida, T. Al-Hilal, F. Ahsan; Texas Tech Univ. Hlth.Sci. Ctr., Amarillo, TX
Institutions:
Texas Tech University Health Sciences Center
Analytical Methods for In Vitro Enteral Tube Drug Delivery Testing
Category:
Oral Delivery for Food and Pharma
Presenters:
Alicia Hoover
Authors:
<b>A. S. Hoover</b><sup>1</sup>, A. Wokovich<sup>1</sup>, P. Chitranshi<sup>1</sup>, M. Momot<sup>1</sup>, K. Tyner<sup>2</sup>; <sup>1</sup>Food and Drug Admin., St. Louis, MO, <sup>2</sup>Food and Drug Admin., White Oak, MD
Institutions:
Food and Drug Administration
Anti-cancer Effects of Combining Drugs and Gene Agents using Aptamer Conjugated Liposomes For Co-targeting Cancer Cells And Cancer Stem-like Cells
Category:
Nucleic Acid Delivery
Presenters:
Keun-Sik Kim
Authors:
<b>K-S. Kim</b><sup>1</sup>, S-M. Lee<sup>1</sup>, H-B. Park<sup>1</sup>, J. S. Park<sup>2</sup>, D-M. Kim<sup>3</sup>, D-E. Kim<sup>3</sup>; <sup>1</sup>Konyang Univ., Daejeon, Korea, Republic of, <sup>2</sup>New York Univ. Sch. of Med., New York, NY, <sup>3</sup>Konkuk Univ., Seoul, Korea, Republic of
Institutions:
Konyang University
Anti-infection Vaginal Patch using Nano Fiber Loaded Acyclovir
Category:
Micro- and nanoparticle Delivery
Presenters:
Elnaz Ahani
Authors:
<b>E. Ahani</b>; North Carolina A&T state Univ., Greensboro, NC
Institutions:
North Carolina A&T state university
Antitumor Efficacy Of Liposomal Dexamethasone In An Advanced Mouse Model Of Multiple Myeloma
Category:
Micro- and nanoparticle Delivery
Presenters:
Raymond Schiffelers
Authors:
A. Deshantri<sup>1</sup>, M. Fens<sup>2</sup>, B. Metselaar<sup>3</sup>, G. Storm<sup>2</sup>, S. Mandhane<sup>4</sup>, T. Mutis<sup>5</sup>, A. Martens<sup>5</sup>, R. Groen<sup>5</sup>, <b>R. Schiffelers</b><sup>1</sup>; <sup>1</sup>Univ. Med. Ctr. Utrecht, Utrecht, Netherlands, <sup>2</sup>Utrecht Univ., Utrecht, Netherlands, <sup>3</sup>Enceladus Pharmaceuticals, Naarden, Netherlands, <sup>4</sup>Sun Pharma, Baroda, India, <sup>5</sup>VU Med. Ctr., Amsterdam, Netherlands
Institutions:
University Medical Center Utrecht
Application Of A Barrier Membrane Coating To Reduce The Weight Of Metformin HCl Extended Release Tablets
Category:
Oral Delivery for Food and Pharma
Presenters:
MANISH RANE
Authors:
<b>M. RANE</b><sup>1</sup>, V. AMBUDKAR<sup>2</sup>, L. MARTIN<sup>1</sup>, N. TAYADE<sup>3</sup>, S. DAMLE<sup>2</sup>, A. RAJABI-SIAHBOOMI<sup>1</sup>; <sup>1</sup>COLORCON INC., HARLEYSVILLE, PA, <sup>2</sup>COLORCON ASIA PVT. LTD., GOA, India, <sup>3</sup>COLORCON ASIA PVT. LTD, GOA, India
Institutions:
COLORCON INC.
Application Of An In-vitro Chewing Method To Assess The Effect Of Storage Conditions On The Chewing Resistance And Drug Release Properties Of An Abuse-deterrent Solid Oral Extended-release Opioid
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Anna Externbrink
Authors:
<b>A. Externbrink</b>, A. S. Hoover; Div. of Pharmaceutical Analysis, Office of Testing and Res., Office of Pharmaceutical Quality, Food and Drug Admin., St. Louis, MO
Institutions:
Division of Pharmaceutical Analysis, Office of Testing and Research, Office of Pharmaceutical Quality, Food and Drug Administration
Application Of Mechanistic Oral Absorption Modeling To Predict In Vivo Drug Disposition
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Suneet Shukla
Authors:
<b>S. Shukla</b>, T. K. Ghosh, P. R. Seo; US Food and Drug Admin., Silver Spring, MD
Institutions:
US Food and Drug Administration
Application of the ClassicDiels-Alder Reaction for Production of Antibody-Drug Conjugates
Presenters:
James Christie
Authors:
<b>J. Christie</b><sup>1</sup>, A. St. Amant<sup>2</sup>, F. Huang<sup>1</sup>, J. Lin<sup>1</sup>, D. Lemen<sup>1</sup>, S. Florinas<sup>1</sup>, S. Mao<sup>1</sup>, C. Fazenbaker<sup>1</sup>, H. Zhong<sup>1</sup>, J. Harper<sup>1</sup>, B. Vijayakrishnan<sup>3</sup>; <sup>1</sup>Medimmune, Gaithersburg, MD, <sup>2</sup>Univ. of California, Santa Barbara, CA, <sup>3</sup>Spirogen, Inc, London, United Kingdom
Institutions:
Medimmune