Annual Meeting Archives | Controlled Release Society (CRS)

2018

Novel Glucosylceramide Synthase Inhibitor Based Prodrug Copolymer Micelles for Delivery of Doxorubicin

Category:

Micro- and nanoparticle Delivery

Presenters:

Jieni Xu

Authors:

J. Xu, J. Sun, Y. Huang, S. Li; Univ. of Pittsburgh, Pittsburgh, PA

Institutions:

University of Pittsburgh

Novel Hollow Microneedle Can Deliver Large Volume For Intradermal Vaccination.

Category:

Topical and Transdermal Delivery

Presenters:

YOSHIHIRO KODAMA

Authors:

Y. KODAMA1, I. Takase1, S. Naito2; 1TOPPAN PRINTING Co., LTD., Saitama, Japan, 2Natl. Inst. of Infectious Diseases, Tokyo, Japan

Institutions:

TOPPAN PRINTING Co., LTD.

Novel Hollow Pegylated Encapsulin Nanoparticles For The Incorporation Of Hydrophilic Compounds

Category:

Micro- and nanoparticle Delivery

Presenters:

Seiichi Sonotaki

Authors:

S. Sonotaki, T. Takami, K. Noguchi, M. Yohda, Y. Murakami; Tokyo Univ. of Agriculture and Technology, Tokyo, Japan

Institutions:

Tokyo University of Agriculture and Technology

Novel Methotrexate Conjugated Pectin Nanoparticles Containing Fluoxetine as Chemosensitizer for Colon-targeted Delivery

Category:

Oral Delivery for Food and Pharma

Presenters:

Kinjal Parikh

Authors:

K. J. Parikh, B. Patel, K. K. Sawant; The M S Univ. of Baroda, Vadodara, India

Institutions:

The M S University of Baroda

Novel Oligoethyleneglycol-based Dense Hydroxyl-terminated Dendrimer Peneterates Impaired Blood Brain/retinal Barrier And Targets Neuroinflammation

Category:

Micro- and nanoparticle Delivery

Presenters:

Rishi Sharma

Authors:

R. Sharma, A. Sharma, Z. Zhang, S. Kambhampati, K. Liaw, J. E. Porterfield, L. DeRidder, K. Lin, S. Kannan, R. M. Kannan; Johns Hopkins Sch. of Med., Baltimore, MD

Institutions:

Johns Hopkins School of Medicine

Novel Peptides Designed By A Rational Approach Show Higher Binding Affinity Towards CD13 Than The Known CNGRC(C1-C5) Peptide Ligand

Category:

Delivery of Proteins, Peptides, and Vaccines

Presenters:

Xiaoling Li

Authors:

M. Uddin, X. Li, H. Joo, J. Tsai, L. Wrischnik, B. Jasti; Univ. of the Pacific, Stockton, CA

Institutions:

University of the Pacific

Novel pH-triggered, Fluorescent, Mesoporous Silica Nanoparticles For Potential Theranostic Applications In Cancer Intervention

Category:

Micro- and nanoparticle Delivery

Presenters:

Lara Freidus

Authors:

L. G. Freidus, P. Pradeep, P. Kumar, T. Marimuthu, Y. E. Choonara, V. Pillay; Univ. of the Witwatersrand, Johannesburg, South Africa

Institutions:

University of the Witwatersrand

Novel Porous Plga Microparticles Formed By "one-step" Emulsification For Pulmonary Drug Delivery

Category:

Micro- and nanoparticle Delivery

Presenters:

Shinnosuke Nishimura

Authors:

S. Nishimura, T. Takami, Y. Murakami; Tokyo Univ. of Agriculture and Technology, Tokyo, Japan

Institutions:

Tokyo University of Agriculture and Technology

Nucleic Acid Carrier Optimization By Bioinspired Chemical Evolution

Presenters:

Ernst Wagner

Authors:

E. Wagner; LMU Univ., Munich, Germany

Institutions:

LMU University

Nucleic Acid-based Systemic Tumor-targeted Nanoparticles By Rolling Circle Replication For Direct Cell Detection And Gene Delivery

Category:

Micro- and nanoparticle Delivery

Presenters:

Sangwoo Han

Authors:

S. Han, J. Lee; Univ. of Seoul, Seoul, Korea, Republic of

Institutions:

University of Seoul

Obtaining Targeted Release Of Viable Freeze-dried Probiotic Strains By Granulation, Extrusion And Fluid Bed Coating

Category:

Oral Delivery for Food and Pharma

Presenters:

Natashia Larsen

Authors:

N. M. Y. Larsen, A. Caglayan, I. Caglayan, D. Bar-Shalom, A. Müllertz; Univ. of Copenhagen, Copenhagen, Denmark

Institutions:

University of Copenhagen

Ocular Diabetic Theranosis Using Smart Contact Lens

Category:

Delivery Science in Cosmetics, Personal Care, and Household Products

Presenters:

Sei Kwang Hahn

Authors:

S. Hahn, D. Keum; POSTECH, Pohang, Korea, Republic of

Institutions:

POSTECH

Ocular Pharmacokinetics Of A Dexamethasone-eluting Contact Lens

Category:

Regional Delivery

Presenters:

Joseph Ciolino

Authors:

J. B. Ciolino1, B. Salvador-Culla1, L. C. Bengani2, R. Tulsan2, A. E. Ross2, D. S. Kohane3; 1Massachusetts Eye & Ear/Harvard Med. Sch., Boston, MA, 2Schepens Eye Res. Inst. at Massachusettes Eye & Ear/Harvard Med. Sch., Boston, MA, 3Boston Children's Hosp./Harvard Med. Sch., Boston, MA

Institutions:

Massachusetts Eye & Ear/Harvard Medical School

On The Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids And siRNA

Category:

Micro- and nanoparticle Delivery

Presenters:

Jayesh Kulkarni

Authors:

J. A. Kulkarni1, M. M. Darjuan1, J. E. Mercer2, S. Chen3, I. V. Zhigaltsev1, R. van der Meel4, J. Thewalt2, Y. C. Tam3, P. R. Cullis1; 1Univ. of British Columbia, Vancouver, BC, Canada, 2Simon Fraser Univ., Vancouver, BC, Canada, 3Integrated Nanotherapeutics, Vancouver, BC, Canada, 4Utrecht Univ. Med. Ctr., Utretcht, Netherlands

Institutions:

University of British Columbia

Optimization Of Alpinia Galanga Oil Loaded Self-nanoemulsifying Drug Delivery System (SNEDDS) Using Design Of Experiments For Fish Anesthesia

Category:

Micro- and nanoparticle Delivery

Presenters:

Nattakanwadee Khumpirapang

Authors:

N. Khumpirapang1, A. Müllertz2, T. Rades2, S. Okonogi3; 1Interdisciplinary Program in NanoSci. and Nanotechnology, Graduate Sch., Chiang Mai, Thailand, 2Faculty of Hlth.and Med. Sci., Univ. of Copenhagen, Copenhagen, Denmark, 3Faculty of Pharmacy, Chiang Mai Univ., Chiang Mai, Thailand

Institutions:

Interdisciplinary Program in Nanoscience and Nanotechnology, Graduate School

Optimization Of A Polymeric Nanoparticle Formulation For Bioresponsive Release Of Doxorubicin

Category:

Micro- and nanoparticle Delivery

Presenters:

Laura Gonzalez-Fajardo

Authors:

L. Gonzalez-Fajardo, L. H. Mahajan, D. Ndaya, R. M. Kasi, X. Lu; Univ. of Connecticut, Storrs, CT

Institutions:

University of Connecticut

Optimization Of Formulation And 3D Geometric Variables Affecting In Vitro Performance Of Modified-release Tablets Manufactured By 3D Printing Method

Category:

Manufacture, Characterization, Measurement, and Stability

Presenters:

Alaadin Alayoubi

Authors:

A. Alayoubi, A. S. Zidan, S. Asfari, C. N. Cruz, M. Ashraf; U.S FDA, Silver Spring, MD

Institutions:

U.S FDA

Optimization Of Lipid Nanoparticles For Intramuscular Administration Of Messenger Ribonucleic Acid (mRNA) Vaccines

Category:

Nucleic Acid Delivery

Presenters:

Kimberly Hassett

Authors:

K. Hassett, K. Benenato, E. Jacquinet, J. Milano, K. Hughes, V. Presnyak, A. Lee, A. Woods, O. Yuzhakov, S. Himansu, A. Lynn, I. McFadyen, J. Senn, M. Stanton, Ö. Almarsson, G. Ciaramella, L. Brito; Moderna Therapeutics, Cambridge, MA

Institutions:

Moderna Therapeutics

Optimization Of Nanoparticle Processing To Improve Bioavailability Based On Quality By Design Approach

Category:

Micro- and nanoparticle Delivery

Presenters:

Sang Yeob Park

Authors:

S. Park1, Z. Kang2, Y. Jin2, J. Park2, H. Lim1, J. Lee1, S-W. Lee1, M-H. Seo1, M. Kim3, S. Jeong4; 1Samyang Biopharmaceuticals Corp., Seongnam, Korea, Republic of, 2Bio-Synectics, Inc., Seoul, Korea, Republic of, 3Pusan Natl. Univ., Pusan, Korea, Republic of, 4Dongguk Univ., Goyang, Korea, Republic of

Institutions:

Samyang Biopharmaceuticals Corp.

Oral Peptide Delivery: The Potential Of Combining Nanoparticle Constructs With Permeation Enhancers

Presenters:

David Brayden

Authors:

D. Brayden1, F. McCartney2, S. Sladek2, D. Hristov2; 12Univ. Coll. Dublin, Dublin, Ireland

Oral Permeability And Pharmacokinetics Of A Pediatric Formulation For The Treatment Of Cerebral Palsy

Category:

Oral Delivery for Food and Pharma

Presenters:

Venkata Yellepeddi

Authors:

V. K. Yellepeddi1, R. Mohammadipur1, C. Sayre2, S. Khambampati3, M. Mishra3, R. Kannan3, H. Ghandehari1; 1Univ. of Utah, Salt Lake City, UT, 2Roseman Univ. of Hlth.Sci., Salt Lake City, UT, 3Johns Hopkins Univ., Baltimore, MD

Institutions:

University of Utah

Orally Active Site-directed Polymer-drug Complexes For Modulating Gut Innate Immune System To Prevent/treat Ulcerative Colitis

Category:

Oral Delivery for Food and Pharma

Presenters:

Siddharth Kesharwani

Authors:

S. S. Kesharwani1, R. Ahmad2, M. A. Bakkari1, M. K. Rajput1, R. Dachineni1, C. K. Valiveti1, G. Bhat1, A. B. Singh2, H. Tummala1; 1Dept. of Pharmaceutical Sci., Coll. of Pharmacy & Allied Hlth.Professions, South Dakota State Univ., Brookings, SD, 2Dept. of Biochemistry and Molecular Biology, Univ. of Nebraska Med. Ctr., Omaha, NE

Institutions:

Department of Pharmaceutical Sciences, College of Pharmacy & Allied Health Professions, South Dakota State University

Orally Delivered Butyrate-functionalized Nanovehicles To Overcome Multiple Barriers And Insight Into “Easy Entry, Hard Exit” Of Active Targeting System In Intestinal Absorption

Category:

Micro- and nanoparticle Delivery

Presenters:

Lei Wu

Authors:

L. Wu, Y. Huang; Sichuan Univ., Chengdu, China

Institutions:

Sichuan University

Organic-inorganic Hybrid Core-shell Particles Made From Biodegradable Coacervate Droplets For Bone Tissue Engineering

Category:

Micro- and nanoparticle Delivery

Presenters:

Syuuhei Komatsu

Authors:

S. Komatsu1, Y. Ikedo1, T-A. Asoh2, R. Ishihara1, A. Kikuchi1; 1Tokyo Univ. of Sci., Tokyo, Japan, 2Osaka Univ., Osaka, Japan

Institutions:

Tokyo University of Science

Osmotic Formulation As Api-Agnostic, Plug-and-play Controlled Release Platform

Category:

Oral Delivery for Food and Pharma

Presenters:

Khek-Khiang (Gary) Chia

Authors:

K-K. Chia, J. DiNunzio, G. Bredael, D. Carroll, P. Gupta, D. Harris, J. Klinzing, Y. Liu, J. Ormes, S. Patel, B. Regler, K. Reuter; Merck & Co., Inc., Kenilworth, NJ

Institutions:

Merck & Co., Inc.