Annual Meeting Archives | Controlled Release Society (CRS)

2016

Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibodies

Category:

Peptides, Proteins, and Vaccines

Authors:

C. WANG (1), Y. Ye (1), G. Hochu (2), Z. Gu (1)

Institutions:

(1) University of North Carolina at Chapel Hill, U.S.A.; (2) NCSU, U.S.A.

Enhancement of EPR effect in nanomedicine with nitric oxide-releasing liposome

Category:

Physical Oncology: Modulating Tumor Microenvironment for Drug Delivery

Authors:

Y. KATAYAMA (1), T. Yoshikawa (1), A. Kishimura (1)

Institutions:

(1) Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Japan

Enhancement of Tableting Properties of a Poorly Compressible, High-dose Drug by Melt Granulation: An Application of QbD Approach

Category:

Oral Delivery

Authors:

P. VAINGANKAR (1)

Institutions:

(1) Institute of Chemical Technology, India

Enhancing Blood Perfusion in Tumor Tissue by preventing Tumor associated Thrombosis using oral Heparin to improve the Distribution of Anti-cancer drugs

Category:

Physical Oncology: Modulating Tumor Microenvironment for Drug Delivery

Authors:

Y. BYUN (1), J. Choi (1), T. Al Hilal (1)

Institutions:

(1) College of Pharmacy, Seoul National University, Korea

Enteric Coating of Micronized API Particles using a Wurster Fluid-Bed Process

Category:

Delivery Technologies in Nutraceuticals, Food, and Oral Products

Authors:

C. LEUNG (1), A. Trementozzi (1), P. Zawaneh (1), Y. Lin (1), E. Irdam (1), S. Karki (1)

Institutions:

(1) Biogen, U.S.A.

Enzymatic and Anti-Tumorigenic Effect of PH20-Expressing Exosome

Category:

Thinking Outside the Box Delivery Technologies: Nanocarriers from Nature

Authors:

Y. HONG (1), I. Kim (1), Y. Yang (1)

Institutions:

(1) Korea Institute of Science and Technology, Korea

Evaluation of Acid-labile PAMAM-Doxorubicin Conjugates on an in vitro Lung Adenocarcinoma Model and their Pseudo-Solution Formulation in Pressurized Metered-Dose Inhalers

Category:

Local Drug Delivery

Authors:

Q. ZHONG (1), S. da Rocha (1)

Institutions:

(1) Virginia Commonwealth University, U.S.A.

Evaluation of Efficacy and Toxicity of a Bone-targeted pH-sensitive Liposomal Formulation Containing Doxorubicin in an Animal Model of Breast-metastatic Tumor in Bones

Category:

Preclinical Science Challenges to Drug Delivery

Authors:

D. DOS SANTOS FERREIRA (1), B. Oliveira (1), C. Farrar (1), P. Caravan (1), M. Oliveira (2), A. Guimaraes (1)

Institutions:

(1) Massachusetts General Hospital/Harvard Medical School, U.S.A.; (2) Universidade Federal de Minas Gerais, Brazil

Evaluation of EUDRAGIT® NM 30 D as a Binder in Drug Layering on Pellets

Category:

Oral Delivery

Authors:

J. AMRUTKAR (1), S. JOSHI (1), S. DOKE (1)

Institutions:

(1) EVONIK INDIA PRIVATE LIMITED, India

Evaluation of Fractional Laser Ablation for the Controlled Transdermal Delivery of Paliperidone and the Development of a Mathematical Model for Laser-Assisted Drug Transport

Category:

Transdermal Delivery

Authors:

C. SERNA JIMENEZ (1), Y. Kalia (1), A. Lopez Castellano (2), V. Merino Sanjuan (3), I. Alberti (1)

Institutions:

(1) University of Geneva, Switzerland; (2) Universidad CEU Cardenal Herrera, Spain; (3) Universidad de Valencia, Spain

Evaluation of in vitro evaporation profile of a natural insect repellent (citronella oil) impregnate in mesoporous silica

Category:

Delivery Technologies in Cosmetics, Personal Care, and Household Products

Authors:

N. MENDOZA MUÑOZ (1), B. JAIME ESCALANTE (2), J. GONZALEZ GONZALEZ (1)

Institutions:

(1) UNIVERSIDAD DE COLIMA, Mexico; (2) UNIVERSIDAD AUTONOMA DE NAYARIT, Mexico

Evaluation of in vitro tests to reduce animal testing in drug toxicology studies

Category:

Predictive Modeling in Delivery and Targeting (Scaling: Mouse to Man

Authors:

Probability of Reaching Targets

Institutions:

Stochastic Process in System Distribution)

Evaluation of Newly-Developed Hypromellose Acetate Succinate (HPMCAS) for Spray Dried Solid Dispersions of Poorly-Soluble Drugs

Category:

New Processes, New Materials, New Products

Authors:

Q. SCHWING (1), M. Davis (1), D. Tewari (1), T. Dürig (1)

Institutions:

(1) Ashland Specialty Ingredients, U.S.A.

Ex-Vivo Intraocular Model to Investigate Long-Term Protein stability in the Vitreous Humor

Category:

Parenteral Systemic Delivery of Biopharmaceuticals: Overcoming Product Development and Regulatory Challenges

Authors:

S. PATEL (1), D. Jere (1), J. Stracke (1), U. Altenburger (2), H. Mahler (2)

Institutions:

(1) Pharmaceutical Development and Supplies PTD (Biologics Europe), F. Hoffmann-La Roche Ltd, Basel, Switzerland, Switzerland; (2) Pharmaceutical Development and Supplies PTD (Biologics Europe), F. Hoffmann-La Roche Ltd, Basel, Switzerland, Switzerland

Exosome mimetics-based platform technology for targeted drug delivery and adjuvant-free vaccine

Category:

Thinking Outside the Box Delivery Technologies: Nanocarriers from Nature

Authors:

Y. GHO (1)

Institutions:

(1) POSTECH, Korea

Exploring Cry protein crystals as a platform to display of tubercle antigens

Category:

Peptides, Proteins, and Vaccines

Authors:

M. CHAN (1), M. Lee (1), M. Nair (2), L. Wang (1), J. Turner (3)

Institutions:

(1) The Chinese University of Hong Kong, Hong Kong; (2) Aaron Diamond AIDS Research Center, Rockefeller University, U.S.A.; (3) The Ohio State University, U.S.A.

Exploring MicroRNA Expression Profiles Related to Cell Death Pathways in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine

Category:

Oligonucleotide Delivery: New Applications and Opportunities

Authors:

J. KUO (1), M. Jan (2), C. Lin (2)

Institutions:

(1) Department of Pharmacy, Chia Nan University of Pharmacy and Science, Taiwan; (2) Institute of Microbiology and Immunology, Chung Shan Medical University, Taiwan

Extended Release Cysteamine Nanowafer as an Efficacious Treatment Modality for Corneal Cystinosis

Category:

Ocular Drug Delivery

Authors:

D. MARCANO (1), C. Shin (1), B. Lee (2), L. Isenhart (1), F. Li (1), J. Jester (2), S. Pflugfelder (1), J. Simpson (2), G. Acharya (1)

Institutions:

(1) Baylor College of Medicine, U.S.A.; (2) University of California, U.S.A.

Fabrication of starch-based nanofibrous mats for wound healing applications

Category:

Tissue Engineering

Authors:

P. WADKE (1), P. Dandekar Jain (1), V. Vaghmare (1), R. Jain (1)

Institutions:

(1) Institute of Chemical Technology, India

Category:

Integration of Imaging and Drug Delivery

Authors:

K. SHIRAISHI (1), K. Kawano (2), Y. Maitani (2), M. Yokoyama (1)

Institutions:

(1) The Jikei University School of Medicine, Japan; (2) Hoshi University, Japan

Fast track development applied to softgel formulation using quality by design (QbD)

Category:

Oral Delivery

Authors:

V. PLASSAT (1), S. de Paiva Lacerda (1), B. Hilbold (1)

Institutions:

(1) Catalent Pharma Solutions, France

FcBP-modified Nanoparticles Transport across the Intestinal Epithelium

Category:

Oral Delivery

Authors:

M. YU (1), Y. Yang (1), D. Xia (1), C. Zhu (1), S. Guo (1), Y. Gan (1)

Institutions:

(1) Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China

Feasibility of subcutaneous entecavir implants for chronic hepatitis B treatment

Category:

Parenteral Systemic Delivery of Biopharmaceuticals: Overcoming Product Development and Regulatory Challenges

Authors:

S. HENRY (1), S. Barrett (1), S. Forster (1), R. Teller (1), Z. Yang (1), M. Gindy (1)

Institutions:

(1) Merck and Co., U.S.A.

Flame Retardant Encapsulation for Preparation of Nanofoams

Category:

Encapsulation and Controlled Release for Industrial Applications

Authors:

L. CHEN (1), A. Kelly-Rowley (1), S. Bunker (1), S. Costeux (1)

Institutions:

(1) The Dow Chemical Company, U.S.A.

Flexible Formulating for Problem Therapeutics

Category:

Ocular Drug Delivery

Authors:

R. GROVES (1), P. Seaman (1)

Institutions:

(1) Midatech Pharma, United Kingdom