Annual Meeting Archives

2016

Heterogeneity in Cervical Tumor Microenvironment Significantly Impacts the Delivery of a Heat-Activated Thermosensitive Liposome Formulation of Cisplatin
Category:
Overcoming Biological Barriers in Drug Delivery
Authors:
Y. DOU (1), N. Chaudary (2), M. Dunne (1), H. Huang (1), D. Jaffray (2), M. Milosevic (2), C. Allen (1)
Institutions:
(1) University of Toronto, Canada; (2) Princess Margaret Cancer Center, Canada
High Capacity GCPQ Polymer Nanoemulsion Allows Efficient Delivery of Disulfiram for Cancer Therapy
Category:
Preclinical Science Challenges to Drug Delivery
Authors:
E. ABD KADIR (1), A. Schatzlein (1), I. Uchegbu (1)
Institutions:
(1) UCL School of Pharmacy, University College London, United Kingdom
HIGH EFFICIENT PHOTODYNAMIC THERAPY USING GAS GENERATING NANOPARTICLE AT TUMOR EXTRACELLULAR pH
Category:
Local Drug Delivery
Authors:
J. LEE (1), E. Ku (1), D. Kwag (1)
Institutions:
(1) Department of Biotechnology, The Catholic University of Korea, South Korea
High Intensity Focused Ultrasound Hyperthermia for Enhanced Macromolecular Delivery
Category:
Physical Oncology: Modulating Tumor Microenvironment for Drug Delivery
Authors:
N. FRAZIER (1), A. Payne (1), J. De Bever (1), C. Dillon (1), A. Ghandehari (1), N. Subrahmanyam (1), H. Ghandehari (1)
Institutions:
(1) University of Utah, U.S.A.
High Supersaturation and Rapid Transcellular Permeation of Benzodiazepines using Prodrugs
Category:
Overcoming Biological Barriers in Drug Delivery
Authors:
D. RAUTIOLA (1), M. Kapoor (1), N. Cheryala (1), G. Georg (1), J. Cloyd (1), R. Siegel (1)
Institutions:
(1) University of Minnesota, U.S.A.
High-throughput synthesis and characterization of microcapsules
Category:
Manufacture, Characterization, Stability, and Regulatory Aspects
Authors:
J. PAUL (1), E. Bauters (1), P. Castelein (1), T. Parasote (1), G. Rivero (2), S. Cakir (2), F. Du Prez (2)
Institutions:
(1) Flamac, a division of SIM, Belgium; (2) Ghent University, Belgium
Hyaluronate - Upconversion Nanoparticle Conjugate for Deep Tissue Photomedicine
Category:
Transdermal Delivery
Authors:
S. HAN (1), H. Kim (1), S. Hahn (1)
Institutions:
(1) POSTECH, Korea
Hyaluronic acid ion pairing nanoparticles for targeted tumor therapy
Category:
Encapsulation and Controlled Release for Industrial Applications
Authors:
W. LI (1)
Institutions:
(1) West China School of Pharmacy, Sichuan University, China
Hydrogel-forming Microneedles for Drug Delivery and patient monitoring
Category:
Transdermal Delivery
Authors:
R. DONNELLY (1)
Institutions:
(1) Queen's University Belfast, United Kingdom
Hydrophobic prodrug nanoparticle delivery of anticancer molecularly targeted drug combinations increases plasma drug exposure and antitumor efficacy in preclinical models
Category:
Parenteral Systemic Delivery of Biopharmaceuticals: Overcoming Product Development and Regulatory Challenges
Authors:
B. LIBOIRON (1), P. Tardi (1), S. Xie (1), L. Wan (1), W. Lui (1), L. Mayer (1)
Institutions:
(1) Celator Pharmaceuticals Corp., Canada
Hydrophobized Microgels for the Delivery of Antipsychotic Drugs to the Brain
Category:
Overcoming Biological Barriers in Drug Delivery
Authors:
M. SIMPSON (1), Y. Katare (1), S. Kooner (1), N. Smeets (1), R. Mishra (1), T. Hoare (1)
Institutions:
(1) McMaster University, Canada
Hyperthermia-induced Triggered Release of Cisplatin from Thermosensitive Liposomes and Changes in Tumor Microenvironment in Non-Small Cell Lung Carcinoma
Category:
Physical Oncology: Modulating Tumor Microenvironment for Drug Delivery
Authors:
Y. DOU (1), M. Dunne (1), H. Huang (1), T. Mckee (2), D. Jaffray (2), C. Allen (1)
Institutions:
(1) University of Toronto, Canada; (2) Princess Margaret Cancer Center, Canada
Hyperthermia-triggered release of cisplatin from thermosensitive liposomes improves local control of triple-negative breast cancer tumours
Category:
Overcoming Biological Barriers in Drug Delivery
Authors:
M. DUNNE (1), Y. Dou (1), T. Spence (1), S. Gontijo (2), C. Allen (1)
Institutions:
(1) University of Toronto, Canada; (2) Universidade Federal de Minas Gerais, Brazil
Hypoxia-responsive siRNA delivery system for tumor-targeted therapy
Category:
Oligonucleotide Delivery: New Applications and Opportunities
Authors:
L. KANG (1), B. Fan (1), W. Huang (1), Q. Wang (1), M. Jin (1), Z. Gao (1)
Institutions:
(1) Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, China
Hypromellose as a solubility enhancer for poorly soluble drugs
Category:
New Processes, New Materials, New Products
Authors:
K. SHIN (1), S. Lee (1), J. Son (1)
Institutions:
(1) Lotte Fine Chemicals, Korea
Imaging guided Therapeutic Modulation of Hepatocellular Carcinoma using Two Complementary MicroRNAs
Category:
Integration of Imaging and Drug Delivery
Authors:
S. MULLICK CHOWDHURY (1), T. Wang (1), S. Bachawal (1), R. Devulapally (1), R. Paulmurugan (1), J. Willamann (1)
Institutions:
(1) Stanford University, U.S.A.
Impact of Crystallization Kinetics on the Distribution of Chemical Components in Monodisperse Microparticles
Category:
Manufacture, Characterization, Stability, and Regulatory Aspects
Authors:
A. BALDELLI (1)
Institutions:
(1) University of Alberta, Canada
Impact of hot and wet granulation techniques on Compritol® 888 ATO lipid matrices for extended release of highly water soluble high dose API
Category:
Oral Delivery
Authors:
K. DESHMUKH (1), C. Kapadia (1), A. Shrivastava (1), G. Khanvilkar (1), P. Vaingankar (2), P. Amin (2)
Institutions:
(1) Gattefosse India Pvt. Ltd., India; (2) Institute of Chemical Technology, India
Impact of Pore Forming Agents &amp
Category:
amp
Authors:
Coating Process Conditions on Drug Release from Pellets Coated with Ethylcellulose Sustained Release Coatings
Institutions:
Oral Delivery
Implantable Poly(DL-lactide-co-glycolide) loaded with N-Acetylcysteine prevents severe post-traumatic osteoarthritis
Category:
Tissue Engineering
Authors:
B. KHORSAND-SOURKOHI (1), A. Morris (1), M. Mesghali (1), M. Coleman (1), J. Martin (1), A. Salem (1)
Institutions:
(1) The University of Iowa, U.S.A.
Implantable Pump Actuated by Static Magnetic Field for On-demand Pulsatile Drug Delivery
Category:
Parenteral Systemic Delivery of Biopharmaceuticals: Overcoming Product Development and Regulatory Challenges
Authors:
S. LEE (1), Y. Choy (1)
Institutions:
(1) Seoul National University, South Korea
Improved antitumor therapies using PEGylated TNF-related apoptosis-inducing ligand in combination with established chemotherapeutics
Category:
Peptides, Proteins, and Vaccines
Authors:
S. LIM (1), K. Lee (1)
Institutions:
(1) SungKyunKwan University, Korea
Improving RNAi-mediated Gene Silencing of Chemically Modified siRNA-GalNAc Conjugate Using Phosphate Mimic
Category:
Oligonucleotide Delivery: New Applications and Opportunities
Authors:
R. PARMAR (1), C. Theile (1), J. Willoughby (1), D. Foster (1), J. O’Shea (1), N. Taneja (1), K. Charisse (1), V. Jadhav (1), M. Manoharan (1), M. Maier (1), K. Rajeev (1)
Institutions:
(1) Alnylam Pharmaceuticals, U.S.A.
In situ targeted activation of a glucuronide prodrug using ultrasound-triggered release of composite droplets
Category:
Integration of Imaging and Drug Delivery
Authors:
M. BEZAGU (1), J. CLARHAUT (2), F. MONTI (3), P. TABELING (3), J. COSSY (4), S. PAPOT (5), M. TANTER (1), O. COUTURE (1), S. ARSENIYADIS (4)
Institutions:
(1) Institut Langevin (CNRS, ESPCI, INSERM), France; (2) IC2MP (Université de Poitiers, CNRS), CHU Poitiers, France; (3) MMN (ESPCI, CNRS, UPMC), France; (4) LCO (ESPCI, CNRS, UPMC), France; (5) IC2MP (Université de Poitiers, CNRS), France
In vitro - in silico approach to access the potential of alcohol-induced dose dumping: Ibuprofen case
Category:
Oral Delivery
Authors:
J. PAROJCIC (1), S. Cvijic (1), A. Lipovac (1), M. Lukic (1), S. Beloica (1), I. Aleksic (1)
Institutions:
(1) University of Belgrade - Faculty of Pharmacy, Serbia