Scientifically Speaking
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Introduction: The current mesh implants (Fig. 1) are composed of polypropylene (PP), polyethylene terephthalate (PET), expanded polytetrafluoroethylene (ePTFE) and polyvinylidenefluoride (PVDF).1 Mesh implants have been widely used, but given the number of complications…
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Over the past decades, demand for natural resources has accelerated to the extent that it is now widely considered a serious threat to the proper functioning of economies and societies owing to associated environmental problems such as climate change, biodiversity loss, desertification, and…
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Introduction
Many promising therapeutic compounds suffer from disadvantages such as low bioavailability, rapid clearance, and high systemic toxicity. To overcome these challenges, nanoparticles such as polymersomes can be used as promising drug delivery systems. Polymersomes are vesicles formed by…
IntroductionCorticosteroids such as dexamethasone are the first line of treatment for noninfectious posterior uveitis and are also routinely used for the treatment of age-related macular degeneration (AMD) (Figure 1…
IntroductionNowadays, most of the currently available ocular drugs are administered topically through eye drops,1 but their residence time in the eye is short, about 2 min…
Macromolecular prodrugs (MP), or polymer–drug conjugates, are successful tools of drug delivery investigated broadly toward optimization of pharmacokinetics of drugs.1 Specific advantage is gained when, for example, the polymer increases solubility of the drug or aids in localizing an enhanced…
