Annual Meeting Archives | Controlled Release Society (CRS)

2014

Invited Speaker: Nanomedicines and Theranostics: Image-guided and Targeted Treatments for Individualized and Improved Interventions

Category:

Mini Symposia – Individualized Medicine and Theranostics

Authors:

T. Lammers

Institutions:

Department of Experimental Molecular Imaging, Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Clinic, 52074 Aachen, Germany; Department of Controlled Drug Delivery, MIRA Institute for Biomedical Engineering and Technical Medicine, University of Twente, 7500 AE Enschede, The Netherlands; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands

Invited Speaker: Oral delivery of heparin conjugate

Category:

Innovations in Oral Drug Delivery

Authors:

Youngro Byun and Taslim Al-Hilal

Institutions:

Department of Molecular Medicine and Biopharmaceutical Science, Seoul National University, Seoul 153-741, Republic of Korea2College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea

Invited Speaker: Physico-chemical Challenges of Designing Delivery Systems for Consumer and Industrial Applications

Category:

Controlled Release of Actives in Consumer Products

Authors:

Nilesh Shah, Fanwen Zeng

Institutions:

The Dow Chemical Company, Spring House, PA 19477, USA

Invited Speaker: Recent Innovations in Oral Vaccine Delivery

Category:

Mini Symposia – Advancements to Develop and Delivery Biologics

Authors:

R. T. McLaughlin

Institutions:

Catalent Pharma Solutions, Frankland Road, Blagrove, Swindon, UK

Invited Speaker: Targeting DNA hypermethylation by nanomedicine for acute myeloid leukemia therapy

Category:

Mini Symposia – Cancer Epigenetics, Epigenetic Drugs and Delivery

Authors:

Fei Yan, Na Shen, Jiuxia Pang, and Shujun Liu

Institutions:

The Hormel Institute, University of Minnesota, 801 16th Ave NE, Austin, MN

Invited Speaker: The Biopharmaceutics of Veterinary Drug Delivery

Category:

Mini Symposia - Interspecies Clinical Pharmacology Dosing Concepts

Authors:

Since Biopharmaceutics operates at the interface of pharmaceutics & physiology, we open with a brief review of the anatomy and physiology of the GI tract for common species. This talk highlights the observations and studies that emphasize the similarities and differences in species and routes of administration. From transdermal to oral, examples of formulations for veterinary practice are presented which emphasize a different clinical or pharmacokinetic outcome between species. Included in the case studies are explanations for this difference. We will see that this difference can be predicted (and sometimes eliminated) once we understand the species-specific physiology, and pharmaceutics of the formulation, ie Biopharmaceutics.

Invited Speaker: The Determination of Cost and the Economics for Controlled Release Processes

Category:

Mini Symposia: Micro- and Nano-Encapsulation: From Innovation to Commercialization

Invited Speaker: Zoological Pharmacology: Of Mice and Elephants

Category:

Mini Symposia - Interspecies Clinical Pharmacology Dosing Concepts

Authors:

Robert P. Hunter

Institutions:

Elanco Animal Health, 2500 Innovation Way, Greenfield, IN

Lipid nanoparticles for organ-specific delivery of RNA

Category:

Advances in RNA and DNA Delivery

Authors:

H. Haas, D. Fritz, M. Meng, , L. M. Kranz, K. C. Reuter, M. Diken, S. Kreiter, S. Funari, D. Pawlowska, G. Brezesinski, U. Sahin

Institutions:

Ribological GmbH, 55131 Mainz, Germany; TRON, 55131 Mainz, Germany; Universität Mainz, 55131 Mainz, Germany; HASYLAB, DESY, 26607 Hamburg, Germany; Max-Planck-Institute for Colloids and Interfaces, 14476 Golm, Germany

Mass Spectrometry for Comprehensive Characterization of Controlled Release Systems

Category:

Evaluation and Characterization of Controlled Release Products and Production Processes

Authors:

S. E. Borgos, A. Brunsvik, A. Kristiansen, F. Männle, Ý. Mørch, R. Schmid-Baumberger, K. Vernstad, K. Zahlsen

Institutions:

SINTEF Materials and Chemistry, Sector Biotechnology and Nanomedicine, Trondheim, N-7465, Norway; SINTEF Materials and Chemistry, Sector Materials and Nanotechnology, Oslo, N-0314, Norway

Mucus Penetrating Nanoparticles Improve Drug and Gene Delivery to the Gastrointestinal Tract

Category:

Innovations in Oral Drug Delivery

Authors:

Katharina Maisel, Laura Ensign, Mihika Reddy, Richard Cone, Justin Hanes

Institutions:

Johns Hopkins University, Baltimore, MD, 21231, USA

Multifunctional delivery systems for encapsulated islet cell therapy

Category:

Cells as Delivery Vehicles

Authors:

D. Lavin,, S. Jhunjhunwala,, S. Aresta-DaSilva,, R. Langer and D. Anderson

Institutions:

David H. Koch Institute for Integrative Cancer Research, Department of Chemical Engineering, and Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA; Department of Anesthesiology, Boston Children’s Hospital, Boston, MA, 02115, USA

Nano-Emulsions for Biomedical Imaging

Category:

Novel Development in Formulation, Analytical Chemistry, and Processing in Animal Health and Preclinical Sciences

Authors:

N. Anton, M. Attia, X. Li and Th.F. Vandamme

Institutions:

University of Strasbourg, CNRS 7199, Conception et Applications de Molécules Bioactives, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch Cedex

Nanostructured lipid-based mucoadhesive particles formed from pH responsive vesicles

Category:

Overcoming Barriers in the GI Tract

Authors:

Joanne D. Du, Qingtao Liu, Tri-Hung Nguyen and Ben J. Boyd

Institutions:

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, 3052, Australia

Non-Disruptive Measurement of Encapsulation Efficiency For Hydrophobic Actives

Category:

Evaluation and Characterization of Controlled Release Products and Production Processes

Authors:

Fanwen Zeng, Boris Polanuyer, Inna Shulman

Institutions:

The Dow Chemical Company, 727 Norristown Road, Spring House, PA 19477, USA

Nucleodendrimers for endosomal escape

Category:

Intracellular Delivery of Nucleic Acids and Proteins

Authors:

S. Muro

Institutions:

Institute for Bioscience &amp; Biotechnology Research and Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA

Ocular delivery of a model biopharmaceutical, lacritin, using protein polymers

Category:

Advances in Drug Delivery to the Eye

Authors:

J. A. MacKay W. Wang, P. Hsueh; M. Edman-Woolcott; S.F. Hamm-Alvarez

Institutions:

Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, 90033, U.S.A.; Biomedical Engineering, University of Southern California, Los Angeles, CA, 90033, U.S.A.; Physiology and Biophysics and Ophthalmology, University of Southern California, Los Angeles, CA, 90033, U.S.A.

Platform-Technology Based on Prodrug/Enzyme Systems for Rapid Absorption of Hydrophobic Drugs: Toward Intranasal Treatment of Seizure Emergencies

Category:

Breakthrough Technologies

Authors:

Mamta Kapoor, Ronald A. Siegel,

Institutions:

Departments of Pharmaceutics and Biomedical Eng., University of Minnesota, Minneapolis, MN 55455, USA

Programmable Release of a Water-Soluble Drug from Electrospun Nanofibers for HIV Inhibition

Category:

Innovations in Micro-and Nano-Based Delivery

Authors:

Daniel Carson, and Kim Woodrow

Institutions:

University of Washington-Department of Bioengineering, Seattle, Washington, 98195, United States

Rational design of wet spun monofilaments and multifilament yarns as controlled-release drug delivery systems for biomedical applications

Category:

Breakthrough Technologies

Authors:

D. Lavin, L. Zhang, R. Hopkins, and E. Mathiowitz

Institutions:

Brown University, Providence, RI, 02912, USA; Children’s Mercy Hospital, Kansas City, MO, 64108, USA

Real time Raman imaging to understand dissolution performance of amorphous solid dispersions

Category:

Evaluation and Characterization of Controlled Release Products and Production Processes

Authors:

Francesco Tres, Stephen A. C. Wren, Jonathan W. Aylott, and Jonathan C. Burley

Institutions:

School of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom; Pharmaceutical Development, AstraZeneca, Macclesfield, SK10 2NA, United Kingdom

Redesigning Nutrition Delivery

Category:

Plenary Session

Authors:

David Edwards

Institutions:

Harvard University, U.S.A.

RNAdjuvant®, a novel RNA-based immunomodulator, combines strong immunostimulatory capacities with a favourable safety profile

Category:

Proteins, Peptides, and Vaccines

Authors:

Patrick Baumhof, Regina Heidenreich, Birgit Scheel, Söhnke Voss, Karl-Josef Kallen, Mariola Fotin-Mleczek

Institutions:

CureVac GmbH, Tübingen, 72076, Germany

Synergistic Effect of M Cell Targeting Peptide and Mucoadhesive Vehicle on Induction of Immune Responses in Oral Vaccine Delivery

Category:

Innovations in Oral Drug Delivery

Authors:

B. Singh S. Maharjan, , T. Jiang, , S.K. Kang, , Y.J. Choi , , and C.S. Cho, ,

Institutions:

Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Korea;2Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Korea

Targeted Cellular Interactions of Dendron Micelles using PEG linkers

Category:

Nanoparticles in Tumor Treatment

Authors:

Ryan M. Pearson, Matt Pasko, Marilyn Gaske, Petr Král, and Seungpyo Hong

Institutions:

University of Illinois at Chicago, Chicago, Illinois, 60612, USA